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Forman Christian College (A Chartered University)
Office of Research, Innovation and Commercialization (ORIC)
Chemistry Department
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Issue Date
Title
Author(s)
2018
The assay-guided isolation of chemical constituents from a medicinal plant (Carissa opaca), and the study of their bio activities.
Ahmed, Dr. Dildar
2018
Isolation of natural products from a medicinal plant of Pakistan and their Chemical and Biotechnological studies
Ahmed, Dr. Dildar
;
Malik, Dr. Kauser .A.
2017
Substitution of synthetic polymers with highly biocompatible and inexpensive polymers from renewable sources in formulation of pharmaceuticals
Massey, Shazma
;
Saeed, Dr. M. Iqbal
2015
Isolation of natural products from a medicinal plant of Pakistan and their Chemical and Biotechnological studies
Ahmed, Dr. Dildar
;
Malik, Dr. Kauser .A.
2015
The assay-guided isolation of chemical constituents from a medicinal plant (Carissa opaca), and the study of their bio activities
Ahmed, Dr. Dildar
2016
Synthesis of novel sulfonamide derivatives as inhibitors of ectonucleotidases
Ahmed, Dr. Dildar
;
Rashida, Dr. Mariya A.
2017
DRUG DELIVERY USING CHOLINE BASED GREEN SURFACTANTS
Rahman, Dr. H. Abd U.
2014-08-17
The objective of the present work was to investigate the anti-oxidative potential of methanolic extract of Carissa opaca roots and its fractions in solvents of different polarities. Total phenolic (TPC) and flavonoid (TFC) contents of methanolic extract were 211.95 ± 0.78 μg/mL gallic acid equivalents (GAE) and 8.35 ± 0.21 μg/mL rutin equivalents (RE), respectively. Ethyl acetate contained the highest amounts of both (TFC, 11.8 ± 0.28 RE; TPC, 342.80 ± 0.42 GAE) followed by chloroform fraction (TFC, 7.50 ± 0.14 RE; TPC, 275.85 ± 0.50 GAE). Extract and fractions displayed remarkable DPPH radical scavenging activity. EC50 values of methanolic extract was 0.88 mg/mL, while that of hexane, chloroform, ethyl acetate, n-butanolic and aqueous fractions were 0.58, 0.38, 0.29, 0.36 and 5.83 mg/mL, respectively, ethyl acetate fraction being most potent. The ethyl acetate fraction also showed the highest activity in terms of reducing power, phosphomolybdate and ABTS assays. All the fractions showed fairly good lipid peroxidation inhibitory activity, which remained almost constant over three days. Based on the results it can be concluded that roots of Carissa opaca contains phytochemicals with exploitable antioxidant, free radical scavenging, and lipid peroxidation inhibitory potential.
Chaudhery, Raza
;
Ahmed, Dr. Dildar
;
Parsa, Dar
;
Liaqat, Inam
;
shaban, Muhammad
2014-10-20
Analysis of Phenolic and Flavonoid Contents, and the Anti-Oxidative Potential and Lipid Peroxidation Inhibitory Activity of Methanolic Extract of Carissa opaca Roots and Its Fractions in Different Solvents
Ahmed, Dr. Dildar
;
Saeed, Ramsha
;
Khaizran, Fatima
2014-12-30
COMPARATIVE ANALYSIS OF ANTIMICROBIAL POTENTIAL OF PEEL AND MESOCARP OF LAGENARIA SICERARIA FRUIT EXTRACTS IN VARIOUS SOLVENTS AGAINST CLINICALLY IMPORTANT PATHOGENS
Parsa, Dar
;
Saeed, Ramsha
;
Chaudhery, Raza
;
Waqas, Usama
;
Ahmed, Dr. Dildar
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Author
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Ahmed, Dr. Dildar
22
Rashida, Dr. Mariya A.
12
Iqbal, Jamshed
8
Saeed, Dr. M. Iqbal
8
Saeed, Ramsha
6
Hameed, Abdul
6
Iqbal, Mohammad S.
5
Abbasi, Muhammad Athar
5
Khalid, Hira
5
Nazar, M. F.
.
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