Recent advances in the synthesis and reactivity  of spiro-epoxyoxindoles

Please use this identifier to cite or link to this item: http://digitalrepository.fccollege.edu.pk/handle/123456789/1284

Title:	Recent advances in the synthesis and reactivity of spiro-epoxyoxindoles
Authors:	Monticelli, Serena Castoldi, Laura Touqeer, Dr. Saad Miele, Margherita Urban, Ernst Pace, Vittorio
Keywords:	nucleophilic addition. epoxides, isatins, spiro compounds, Friedel–Crafts reaction,
Issue Date:	7-Jun-2018
Publisher:	springer link
Citation:	Monticelli, S., Castoldi, L., Touqeer, S. et al. Recent advances in the synthesis and reactivity of spiro-epoxyoxindoles. Chem Heterocycl Comp 54, 389–393 (2018). https://doi.org/10.1007/s10593-018-2280-4
Series/Report no.:	Chem Heterocycl Comp 54, 389–393 (2018).;
Abstract:	Spiro-epoxyoxindoles containing an unsubstituted methylene fragment in the oxirane ring are excellent building blocks in organic syn thesis due to the high reactivity conferred by the three-membered oxygenated cycle. In this minireview, a concise survey of the methods of their synthesis and examples of reactivity with carbon and nitrogen nucleophiles is presented, with a particular focus on the stereo chemical aspects. The review covers the literature for the last twenty years.
Description:	https://link.springer.com/article/10.1007/s10593-018-2280-4#citeas
URI:	http://localhost:8080/xmlui/handle/123456789/1284
Appears in Collections:	Pharmacy Department

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