Please use this identifier to cite or link to this item: http://digitalrepository.fccollege.edu.pk/handle/123456789/1284
Title: Recent advances in the synthesis and reactivity of spiro-epoxyoxindoles
Authors: Monticelli, Serena
Castoldi, Laura
Touqeer, Saad
Miele, Margherita
Urban, Ernst
Pace, Vittorio
Keywords: nucleophilic addition.
epoxides,
isatins,
spiro compounds,
Friedel–Crafts reaction,
Issue Date: 7-Jun-2018
Publisher: springer link
Citation: Monticelli, S., Castoldi, L., Touqeer, S. et al. Recent advances in the synthesis and reactivity of spiro-epoxyoxindoles. Chem Heterocycl Comp 54, 389–393 (2018). https://doi.org/10.1007/s10593-018-2280-4
Series/Report no.: Chem Heterocycl Comp 54, 389–393 (2018).;
Abstract: Spiro-epoxyoxindoles containing an unsubstituted methylene fragment in the oxirane ring are excellent building blocks in organic syn thesis due to the high reactivity conferred by the three-membered oxygenated cycle. In this minireview, a concise survey of the methods of their synthesis and examples of reactivity with carbon and nitrogen nucleophiles is presented, with a particular focus on the stereo chemical aspects. The review covers the literature for the last twenty years.
Description: https://link.springer.com/article/10.1007/s10593-018-2280-4#citeas
URI: http://localhost:8080/xmlui/handle/123456789/1284
Appears in Collections:Pharmacy Department

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