Degradation of atorvastatin: (1R,2S,4S,5S)-4-(4-fluorophenyl)-2- hydroperoxy-4-hydroxy-2-isopropyl-N,5-  diphenyl-3,6-dioxabicyclo[3.1.0]hexane- 1-carboxamide

Please use this identifier to cite or link to this item: http://digitalrepository.fccollege.edu.pk/handle/123456789/1564

Title:	Degradation of atorvastatin: (1R,2S,4S,5S)-4-(4-fluorophenyl)-2- hydroperoxy-4-hydroxy-2-isopropyl-N,5- diphenyl-3,6-dioxabicyclo[3.1.0]hexane- 1-carboxamide
Authors:	Ashfaq, Muhammad Tahir, Muhammad Nawaz Khan, Islam Ullah Iqbal, Mohammad S. Arshad, Muhammad Nadeem
Keywords:	single-crystal X-ray study; T = 296 K; mean (C–C) = 0.004 A ̊; R factor = 0.050; wR factor = 0.136; data-to-parameter ratio = 16.8.
Issue Date:	2008
Abstract:	The degradation of atorvastatin calcium in methanol and hydrogen peroxide results in the crystallization of the title compound, C26H24FNO6, which shows several differences compared with the starting compound. In the crystal structure of the title compound, intra- and intermolecular hydrogen bonding is found.
URI:	http://localhost:8080/xmlui/handle/123456789/1564
ISSN:	1600-5368
Appears in Collections:	Chemistry Department

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