Degradation of atorvastatin: (1R,2S,4S,5S)-4-(4-fluorophenyl)-2- hydroperoxy-4-hydroxy-2-isopropyl-N,5- diphenyl-3,6-dioxabicyclo[3.1.0]hexane 1-carboxamide

Please use this identifier to cite or link to this item: http://digitalrepository.fccollege.edu.pk/handle/123456789/2205

Title:	Degradation of atorvastatin: (1R,2S,4S,5S)-4-(4-fluorophenyl)-2- hydroperoxy-4-hydroxy-2-isopropyl-N,5- diphenyl-3,6-dioxabicyclo[3.1.0]hexane 1-carboxamide
Keywords:	single-crystal X-ray study; T = 296 K; mean (C–C) = 0.004 A˚; R factor = 0.050; wR factor = 0.136; data-to-parameter ratio = 16.8
Issue Date:	16-Jul-2008
Publisher:	Acta Crystallographica Section E: Structure Reports Online
Citation:	Ashfaq, Muhammad, et al. "Degradation of atorvastatin:(1R, 2S, 4S, 5S)-4-(4-fluorophenyl)-2-hydroperoxy-4-hydroxy-2-isopropyl-N, 5-diphenyl-3, 6-dioxabicyclo [3.1. 0] hexane-1-carboxamide." Acta Crystallographica Section E: Structure Reports Online 64.8 (2008): o1548-o1548.
Abstract:	The degradation of atorvastatin calcium in methanol and hydrogen peroxide results in the crystallization of the title compound, C26H24FNO6, which shows several differences compared with the starting compound. In the crystal structure of the title compound, intra- and intermolecular hydrogen bonding is found
URI:	http://202.142.177.21/handle/123456789/2205
Appears in Collections:	Chemistry Department

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