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http://digitalrepository.fccollege.edu.pk/handle/123456789/2237| Title: | PREPARATION, CHARACTERIZATION AND BIODISTRIBUTION OF SALICYLIDENE- AND PYRIDOXYLIDENE-THYROXINE COMPLEXES OF TECHNETIUM-99m |
| Authors: | Iqbal, Mohammad S. RIZVI, M. H. NAQVI, A. |
| Issue Date: | 9-Jun-1992 |
| Publisher: | Journal of radioanalytical and nuclear chemistry |
| Citation: | Iqbal, M. S., M. H. Rizvi, and A. Naqvi. "Preparation, characterization and biodistribution of salicylidene-and pyridoxylidene-thyroxine complexes of technetium-99m." Journal of radioanalytical and nuclear chemistry 162 (1992): 139-144. |
| Abstract: | New Schiff bases, salicylidene- and pyridoxylidene-thyroxine have been prepared and characterized. They were labeled with99mTc. The labeling yield of the Schiff bases was over 95%. About 60% of the activity was bound to γ-globulin and albumin fractions when the labled compounds were incubated with a serum sample. The labeled compounds, after i.v. administration to rats, rapidly cleared from blood and excreted into the small intestine. They appeared to behave as hepatobiliary agents. |
| URI: | http://202.142.177.21/handle/123456789/2237 |
| Appears in Collections: | Chemistry Department |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| JRNC1992Thyr.pdf | 275.41 kB | Adobe PDF | View/Open |
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