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DC Field | Value | Language |
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dc.contributor.author | Iqbal, Mohammad S. | - |
dc.contributor.author | Khurshid, Syed J. | - |
dc.contributor.author | Muhammad, Bakhtiar | - |
dc.date.accessioned | 2024-05-24T05:23:07Z | - |
dc.date.available | 2024-05-24T05:23:07Z | - |
dc.date.issued | 2012-04-19 | - |
dc.identifier.citation | Iqbal, Mohammad S., Syed J. Khurshid, and Bakhtiar Muhammad. "Anti-inflammatory and selective COX-2 inhibitory activities of metal complexes of Schiff bases derived from aldoses." Medicinal Chemistry Research 22 (2013): 861-868. | en_US |
dc.identifier.other | DOI | - |
dc.identifier.uri | http://202.142.177.21/handle/123456789/2245 | - |
dc.description.abstract | Mn(II)-, Fe(II)-, Co(II)-, Ni(II)-, and Zn(II)- Schiff base complexes containing anthranilic acid and aldoses as part of the base were prepared and characterized by microanalytical, thermogravimetric, and spectroscopic data. The complexes were found to be four-coordinate, anhydrous, and ML2 type. The spectral and magnetic data indicate a tetrahedral geometry for Mn(II) and Fe(II) complexes, and a planar geometry for Co(II), Ni(II), and Zn(II) complexes. Mn(II) and Zn(II) complexes showed a significant anti-inflammatory activity against kaolin-paw edema. All the complexes exhibited selective inhibition of COX-2 in two different cell models | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Medicinal Chemistry Research | en_US |
dc.subject | Aldoses-derived Schiff bases Schiff base complexes Metal complexes Anti-inflammatory activity COX-2 inhibition | en_US |
dc.title | Anti-inflammatory and selective COX-2 inhibitory activities of metal complexes of Schiff bases derived from aldoses | en_US |
dc.type | Article | en_US |
Appears in Collections: | Chemistry Department |
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MCR2013(1).pdf | 503.96 kB | Adobe PDF | View/Open |
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