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http://digitalrepository.fccollege.edu.pk/handle/123456789/1090
Title: | Lahorenoic Acids A−C, ortho-Dialkyl-Substituted Aromatic Acids from the Biocontrol Strain Pseudomonas aurantiaca PB-St2 |
Authors: | Mehnaz, Samina Saleem, Rahman Shah Zaib Yameen, Basit Pianet, Isabelle Schnakenburg, Gregor Pietraszkiewicz, Halina Valeriote, Fred Josten, Michaele Sahl, Hans-Georg Franzblau, Scott G. Gross, Harald |
Keywords: | Lahorenoic Acids Aromatic Acids Strain Pseudomonas aurantiaca |
Issue Date: | 12-Feb-2013 |
Publisher: | ACS publications |
Citation: | doi.org/10.1021/np3005166 | J. Nat. Prod. 2013, 76, 135−141 |
Series/Report no.: | J. Nat. Prod. 2013, 76, 135−141; |
Abstract: | Three new aromatic acids, named lahorenoic acids A (1), B (2), and C (3), have been isolated along with the known compounds phenazine-1-carboxylic acid (4), 2- hydroxyphenazine-1-carboxylic acid (5), 2-hydroxyphenazine (6), 2,8-dihydroxyphenazine (7), cyclo-Pro-Tyr (8), cyclo-Pro Val (9), cyclo-Pro-Met (10), and WLIP (11) and charac terized from the biocontrol strain Pseudomonas aurantiaca PB St2. The structures of these compounds were deduced by 1D and 2D NMR spectroscopic and mass spectral data interpretation. Compounds 2, 4, and 7 showed moderate antibacterial activity against mycobacteria and other Gram positive bacteria, while 4 was also found to exhibit cytotoxic and antifungal properties. |
URI: | http://localhost:8080/xmlui/handle/123456789/1090 |
Appears in Collections: | School of Life Sciences |
Files in This Item:
File | Description | Size | Format | |
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JNP. aurantiaca. 2013.pdf | 582.61 kB | Adobe PDF | View/Open |
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