Bond Incident Degree (BID) Indices of Line Graphs of some Chemical Structures in Drugs

Abstract

A tremendous amount of drug experiments revealed that there exists a strong inherent relation between the molecular structures of drugs and their biomedical and pharmacology characteristics. Due to the effectiveness for pharmaceutical and medical scientists of their ability to grasp the biological and chemical characteristics of new drugs, analysis of the bond incident degree (BID) indices is significant of testing the chemical and pharmacological characteristics of drug molecular structures that can make up the defects of chemical and medicine experiments and can provide the theoretical basis for the manufacturing of drugs in pharmaceutical engineering. Such tricks are widely welcomed in developing areas where enough money is lacked to afford sufficient equipment, relevant chemical reagents, and human resources which are required to investigate the performance and the side effects of existing new drugs. This work is devoted to establishing a general expression for calculating the bond incident degree (BID) indices of the line graphs of various well-known chemical structures in drugs, based on the drug molecular structure analysis and edge dividing technique, which is quite common in drug molecular graphs.